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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a87180bbcdc5199b86182340633edfdd124fc8b295a21c51eb284294ca2ea3ae' 
  AND token = 'IWE4W/LUbePhn3RXBcKAF14GMIu5r17asQmkKYh4Aqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}