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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'de2657e017e86cf91716ef924a4c0f56afea3646e28300c5a9a95efa4975f856' 
  AND token = 'zte4KO3P8dEGYcdzOcZPwmSktv0tOW464fCBrJv63Qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}