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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '005e4f81b15e056d5ab88c5a71ddcac78cfed42d4db770f9245f127701a259da' 
  AND token = '95enAjetgN122oxA7tpV6Lzr+kBOjr8W24ECD28OUY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}