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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22c4f11126d88d27d9088dddf7092a7913fcbb63901e47227de2b9e1f6e39cef' 
  AND token = '61bv82AaqYEppBr8Q1VSNPnN16i+5nEHzBSFFDTfOQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}