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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7b61b099d279a7108aa3aacfea1778cb3b91122b3622310837f5ac50a518ce47' 
  AND token = 'tp1zq1hV09k+kGifvK/PWTztcN97fs5EFMd3hMq9OaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}