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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '21e46bf9765c62e8ab2a7bec741552eb36b6b75ad19873953e3b240c5908314e' 
  AND token = '11CvzAcMWVNXM0Y84ZLmRG/XT07yqekRcfTGEq4eg7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}