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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '26fd50f1c502d276e57611569ae795b70301b0ccbfaeb815fd889ab929a4c020' 
  AND token = 'z3zzaHWFm1S0v1HXKwlHKRx5lHXWdn3zGkIXUu3Py0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}