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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '90f22b7f44d1499c7992a08601220982a8fc93b30c4b5933c3efb01e25068a48' 
  AND token = 'MD5wMebo1OuXbSzFudRHecnX204Q3cAienSoF0HB2iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}