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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2b08c0141211ca53ac207a355b59ad578e54554a1162abaabd782a651394f5fc' 
  AND token = 'J9HXwVw/rqRxeeGdnLASOB/n/VtzJbO46tW5dZywOeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}