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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'de204bd97bf8eb1e2d851a9badff24f200df7b89d3e7dbf0759b4d7e5a429430' 
  AND token = 'Z8fDgp7Du2yrNP9Yki9SZo+nNhjwevNcFBbYNihf5E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}