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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22feb849c47d8c7a62a83f97c0bb6d18b2b5b1b362eca6a28f71fbebbd9b5d6c' 
  AND token = 'YukvR6GwLBrMw+cbQbXyWPWdEaJr6G3eD926DtbWcnQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}