Sandbox

SELECT 
  1 
FROM 
  cscart_june_setupec_print_temp_designs 
WHERE 
  session_id = 'DR7E-E7HH-IMUX-P3HK-32LS-0CWU-IX9V-GN64' 
  AND product_id = 65 
  AND expires_at > 1781897686 
  AND confirmed = 'Y' 
LIMIT 
  1

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}