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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ec54063f1e1cc3087aa1d166802a808b85c94be78cd45e96ba6b2f5636e94e66' 
  AND token = 'HGg7IHlklxADgtLU7P4CD/RC0kVrUrCdKoDpk755sqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}