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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '065e9215ae211a6f74977c43ad110fb0603df4b50475c21b31559f800b4bc87d' 
  AND token = 'ry1j2UKgz47lu8h1Rs1eitqtF8ELSV8CbCIialh3Ldo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}