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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2e7c703c616d4cd1720e186dc1bc6d8aac3c2ad24e9e72d8acdd7900b281b803' 
  AND token = '8Ay5u+VF9K9dsibX0ZuzaNjJdjhaoQYQqoTH8WMsGUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}