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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '68858121acda6b92367aab08870a4548e1dc60724349e2aa546a1c8ecdc40d0f' 
  AND token = 'o4wNbhANCEahMrvL5eU2Ilsx44sMlUUhRk7qsjEd3oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}