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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '356be9ecbce439aba103ca244e5496834ea4dbeff8c292fecc69ca7b7b657998' 
  AND token = 'YbAgm8imptu02QCmnXxpbebc3vtVMDHTn10cMD7z6ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}