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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bf5a31e38bc4a4ea2ac7ed5e964140214e0bfe56104468f641010edede91f170' 
  AND token = 'hmRhPK71Qgzniy7NrvdEec1SrHK19R1whOEuxaH5S4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}