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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '818620203fcbfdb57922d7b4b721e2836768c06a9b2696543aa6b2400bcbba48' 
  AND token = 'hQoeZxJKUgCKst1um684LATYT35VnU734JV3uXmi1aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}