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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd27024329bc126dcbef9f37236bf86f0225a112efc2d4d928f8e47777e1a6d06' 
  AND token = 'hO6+XdEScoZAXVW423J0TK21fhJPL+xyG8Deiv0BAu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}