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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4490b52d8fe5be395a0aff67a1be6752f125defdf4dc5409715ae3c3d5b8e23a' 
  AND token = '+9K7LwJ0O2T0tGA8Mnb8FfP/v9g5W7eRiMtYdSGyFRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}