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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '820a993c86a0eb2a3cc24ec3b2724c82dea6063640509560443e196fc0d5a255' 
  AND token = 'OSBRBi6uDL8FtBPUIzIIyLa0eykBxTWvf+E5WyWfbJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}