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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1a45caa6cbb0dbddde7ae340275aa123efa7644fb121875b97741f63193aea31' 
  AND token = 'i+x0E+WgxOYfiiJjdA+EUViWWVW7lM8YBnBiGKkyt7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}