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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7b95272efbc2cc18428d7a9165c447b69a66bcf0ae287ab2e1676fabe90ebaaa' 
  AND token = 'ZFUmHJsXn3uie8/QqsC0xMTQELe/Y0/fmpp4qNCfl2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}