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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'af268052c4870f3e564d8f896324884d540e1d7e9585951a336d9b7cbb35b0b3' 
  AND token = 'uOO9LQYyyOZ1gTTKDbYBFxiubI1NeLwrwDiLHdd7jOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}