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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8271c47cdc69a3070134e146041ab24246560686fe5c6af87067a6f748cae465' 
  AND token = 'qiowlzGI+cfnMkY3ASIKHC5AHGYL4cmFyxq7CIR4NFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}