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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '50bb20ccfa8958407e6dd05b6fe768520b4854aed666adcc75a6f48b297cab71' 
  AND token = 'r64sN9pb4L79NtQ/fLrqcXChzfSVV8BhORmn3StvCuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}