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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '435405166e36ef62e5a59160a18591854fe6f2d446ae597f561db73374adec10' 
  AND token = '8LGRX3yZPVF0eTq9kiPdNGuOi18alb3HMNK8fldT354=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}