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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4bc8482782cd932ceb457e56aad47561b72743e3db151784e41ba4944c3a20e2' 
  AND token = 'kvEC8Chwt5LH8+F4hZUNR6PEbM8vIU6Q6WHrIdie9JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}