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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '33013bc788500d0d0a70a35b44c0e0934cac74aa5d0d33b63759d44870689c55' 
  AND token = 's+x4a9RnaiiKxUeavCtYaIOLHF4y7TflfNYFgMUjoHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}