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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e53627934d3f352b876fd6279fc451a88beb6655c940195b9b71646c091241ad' 
  AND token = '7470/tfJiErG4uyEoa5mW6beYtOjXFtq39QcmjRolHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}