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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1293101f363de1f302369e1d6f2d97cce64a52844f4139493ca30eb65bf848f3' 
  AND token = 'xDkNIk8xxBotaK7ZncflmYKGcCK+iVSHDNOnNPhHlPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}