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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e302b508fe9057fb1825c62901deb20ff8d79560810924b3be4d58a996f18b58' 
  AND token = 'rDn5egRoAy8Kpzz91KgDR9gpzf7XK87OQFBxxVqJLQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}