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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8e99081e652efd905832f42e72ec6e9e4efa46ef89dee6a72e19596932426064' 
  AND token = 'KLHRw+gMS0f1xdH3qN+QLv/8EE5YzY7YYUVoPwOs8vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}