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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '288e6e21410b972a35280fdf044fb5676078ec495363511fb50a4507e5273a3d' 
  AND token = 'J2+aeQcN2k3bvVb/TAYKRQoRHTYbFsTFpgi1bsdg35k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}