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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c1ab3725e14fb69b67b2a7cadeb9cc5f4ffc872265f56fc272f5606f2ccdf0bb' 
  AND token = 'jY3ZV3e8u+4LGq8SsFAvkwBnjTV2aFI2d9coPfb3zzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}