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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd823e1bee1cd288e915f6e9d5b0ae5f187d3337a0726b839dff5b0e2bcaf9c19' 
  AND token = 'nQTd0wU9rxwh6YbRgDnE09i5XBW7VLpN+HOEbcJ5B0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}