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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '16ffbdcdea733787eff35e1e164442f92db3ad7be210135edc4f025d512c6917' 
  AND token = 'NSv2tjjxOlPVx1iDl27XcNenSHixGshBBUEI5JYTcMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}