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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7d716f5e2a49296d98e3516afb01efb00beb7522578db3982bd9e90f03753925' 
  AND token = 'ftW3WtMgIjSU+g4EmFxTd584H5RYZjA3g9pZkCIQ3zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}