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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9449ae7fc4f1611a439a8cd8e1bb70117704d475e2871a01e7a87390dd74fcec' 
  AND token = 'V18NupFkm4dVVxQUI/JVQQbF+sFHiK0R8Eyo5TRkB4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}