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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0e8385aa2b3828d70959ccf2de84253e38638b3eb66fc68c294503335fd39efd' 
  AND token = 'M2711rpLDfe+Wx7E2QeHvZBP29Oz+qtZvmFKJMj0DAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}