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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '397fe517a1b7d165bf6ed8481893627b67d708d89228b3c9011a829a458777c0' 
  AND token = 'iTiKDTcjaLWNvDKefm+xTyNXTsFFxTvpUx3W1Ahehyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}