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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '453e248ba5d38afba5d15599f292315b3476266c2eb90b765fb011fefec2bfae' 
  AND token = 'GmKL5Baed4SNCkkJLrgz374osR85cEsdSzI2EE0dI4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}