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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '112ca5a078b8a594090470779c16924a276ce8bbf5a173faeba30a3af66a51c9' 
  AND token = 'WXurmK7kZ2AjvSwE16dwy94alXJzZcXDFkfN8rpOxgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}