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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c78684e7ab4f353cf6173779cc51949b50cd39165a4556b8c695acf20a7fdc87' 
  AND token = 'glZiDwMnFOMWcHQFxxux2wi1swO7lYgQh2rZQSiSvdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}