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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '40543717e5e04f0884a98da525c9d3045d8696dfb242f6533a4b5b2243492782' 
  AND token = 'CJR7kVSY4N49SHn0I9jyPiEMcE5+AS+uRGNaxJXxu/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}