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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '38b4863a52f81b0c45274b0c8cac3e2ad9e1276e58eb814ad002c4fda8d5ab51' 
  AND token = '528p077ugeeAe8OBQGbMHuD1m1cmgCg+aE5IdgERCQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}