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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9de74e6216aadc494368a37527cca1fc7359da12e5b955a2409e7ba06dc2083b' 
  AND token = 'mB5AshtsJqweoD4pFNH830Xm5MRjqokhDrDVWPlYqWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}