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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2c18562c0d4e6820a3e215612953893de69d20e30b270c9382d4c540ba0b4295' 
  AND token = 'hGhDBCIH2WXRVaKAPAzgbrekckkp16z3W0SQ8UMvKYY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}