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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '49c875057b075ce562e9fd83fe6604c462a7e2e1c61462c022d9ff1157d9e593' 
  AND token = 'CukGDYBQbrl7XIZMLBEtJv8qIkT3vMix11bEopNcZko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}